Coronavirus Vaccine

COVID-19 Vaccines Banner


Scheduling a COVID-19 vaccine appointment is easy! 

  • Visit:
  • Search for zip code 27278
  • Choose a time and date that works for your schedule!
  • Call 919-913-8088 to register by phone. Spanish and other languages available. 

Página en Español:

Visit our Multilingual Resources Page for resources in many languages:

END COVID 820x312

As of April 7, 2021,*everyone ages 16 and up, is eligible to get vaccinated



Getting a free COVID-19 vaccine is simple and convenient! We have walk-in clinics every week:

  • Monday 2 pm - 7pm 
  • Wednesday 8 am - 1 pm 
  • Thursday 2 pm - 7 pm 
  • Friday 8 am - 1 pm

LOCATION: Whitted Human Services Center at 300 West Tryon St., Hillsborough, NC 27278

Free and no ID or insurance required.

If you would like to schedule an appointment at a time and date that is convenient for you, call 919-913-8088 or visit Search for zip code 27278.


Pop-up vaccine clinics are open to all community members ages 18 and older.
We encourage you to register by calling 919-913-8088 or by visiting Walk-ins are also welcome!


Mebane Mobile Homes202 Supper Club Rd., Mebane, NCThursday, May 13 from 4:00 pm to 7:00 pmPartnership with El Centro Hispano
Mt. Zion AME Church5125 Hwy 86 N, HillsboroughSaturday, May 15 from 9 a.m. to 1 p.m.Pfizer first doses available.
Ridgewood Mobile HomesCorner of Deerfield Trail and Ridgewood Rd. in Chapel Hill, NC 27516Thursday, May 20 from 4:00 pm to 7:00 pmPartnership with El Centro Hispano



Vaccine Providers approximate to Orange County:

Vaccine ProviderWeb SitePhone Number
Orange County Health
UNC Health
Piedmont Health Services
Hillsborough Pharmacyhttps://www.hillsboroughpharmacync.com919-245-1212
Duke Health you are a Duke MyChart user, you can check regularly to view appointment availability.
Cone Health
Durham Veterans Affairs (VA)
Chapel Hill Pediatrics and Adolescentshttp://www.chapelhillpeds.com919-933-3473
Greensboro Mass Vaccination Site

Tarheel Town PharmacyEmail ttpharmacy17@gmail.com919-240-7827
Walgreenshttps://www.walgreens.comCall individual stores.

Walgreens Locations offering COVID-19 Vaccines:

1670 Martin Luther King, Jr. Blvd. Chapel Hill
1500 E. Franlin St.Chapel Hill
801 Mebane Oaks Rd.Mebane
1106 Environ WayChapel Hill
200 US Highway 70 EHillsborough
602-G Jones Ferry RoadCarrboro

*NCDHHS maintains a list of all the vaccination sites in North Carolina:

Please do not double book, but rather either go through one provider or another.

Learn more about the COVID-19 Vaccination Plan

More information from the Orange County Health Department 
Press Release: English, Español, Chinese, Burmese, Karen

More information from the North Carolina Department of Health and Human Services here:

More information from the CDC here:

When Can You Get the Shot Banner

Instagram Post GROUP 5_2web

Screen Shot 2020-12-30 at 5.04.03 PM

Vaccine (shots) are one of the tools we have to fight the COVID-19 pandemic. 

To stop this pandemic, we need to use all of our prevention tools. Vaccines are one of the most effective tools to protect your health and prevent disease. Vaccines work with your body’s natural defenses so your body will be ready to fight the virus, if you are exposed (also called immunity). Other steps, like wearing a mask that covers your nose and mouth and staying at least 6 feet away from other people you don’t live with, also help stop the spread of COVID-19.

Studies show that COVID-19 vaccines are very effective at keeping you from getting COVID-19. Experts also think that getting a COVID-19 vaccine may help keep you from getting seriously ill even if you do get COVID-19. These vaccines cannot give you the disease itself.

Screen Shot 2020-12-30 at 5.19.08 PMDifferent types of COVID-19 vaccines are available.

Most of these vaccines are given in two shots, one at a time and spaced apart. The first shot gets your body ready. The second shot is given at least three weeks later to make sure you have full protection. If you are told you need two shots, make sure that you get both of them. The vaccines may work in slightly different ways, but all types of the vaccines will help protect you.




Vaccine Safety Banner

Great care has been taken to ensure COVID-19 vaccines are safe and effective.

Scientists had a head start. Although the vaccines were developed quickly, they were built upon years of work in developing vaccines for similar viruses.

Testing was thorough and successful. More than 70,000 people participated in clinical trials for two vaccines to see if they are safe and effective. To date, the vaccines are nearly 95% effective in preventing COVID-19 with no safety concerns.

There is no COVID-19 virus in the vaccine. The vaccine imitates the infection so that our bodies think a germ like the virus is attacking. This creates the antibody defenses we need to fight off COVID-19 if and when the real germ attacks.

No major side effects. Some people may have temporary reactions after being vaccinated, such as swelling from the injection, tiredness or feeling off for a day or two.


Vaccine Information Banner

Where can I find answers to my vaccine questions?

The North Carolina COVID-19 Vaccine Help Center 

Call: 888-675-4567

Callers can get help with general COVID-19 vaccine questions by calling 888-675-4567 for information on eligibility groups, clinical questions about the vaccine, how to find vaccine locations, and transportation services.

The COVID-19 vaccine help center supports English and Spanish calls, and TTY. Callers will be able to select call back assistance where they receive a call when agents are available instead of waiting in line for an agent. The language line will be available for all other languages needed. 

Monday through Friday from 7 a.m. until 7 p.m.
Saturday and Sunday from 8 a.m. until 4 p.m.

 Check out these pages for answers to  frequently asked questions:

Or call the NCDHHS COVID-19 hotline at  2-1-1 or 888-892-1162

COVID-19 Vaccine Resources for Healthcare Providers

COVID-19 Vaccination Communication Toolkit for Medical Centers, Clinics, and Clinicians

ADA Coronavirus (COVID-19) Center for Dentists

 Long Term Care Facilities COVID-19 Toolkit  

COVID-19 Vaccine Resources for the General Public

COVID-19 Vaccine Overview 

CDC Frequently Asked Questions About COVID-19 Vaccines

After the Shot Header

Source: CDC 

COVID-19 vaccination will help protect you from getting COVID-19. You may have some side effects, which are normal signs that your body is building protection. These side effects may affect your ability to do daily activities, but they should go away in a few days.

Common side effects

On the arm where you got the shot:

  • Pain
  • Swelling

Throughout the rest of your body:

  • Fever
  • Chills
  • Tiredness
  • Headache

Helpful tips

If you have pain or discomfort, talk to your doctor about taking an over-the-counter medicine, such as ibuprofen or acetaminophen.

To reduce pain and discomfort where you got the shot:

  • Apply a clean, cool, wet washcloth over the area.
  • Use or exercise your arm.

To reduce discomfort from fever:

  • Drink plenty of fluids.
  • Dress lightly.

When to call the doctor

In most cases, discomfort from fever or pain is normal. Contact your doctor or healthcare provider:

  • If the redness or tenderness where you got the shot increases after 24 hours
  • If your side effects are worrying you or do not seem to be going away after a few days
  • If you get a COVID-19 vaccine and you think you might be having a severe allergic reaction after leaving the vaccination site, seek immediate medical care by calling 911. Learn more about COVID-19 vaccines and rare severe allergic reactions.

V-Safe app: after vaccination health checker

Use your smartphone to tell the CDC about any side effects after getting the COVID-19 vaccine.

Screen Shot 2021-02-19 at 8.51.22 AM Opens in new window
This 1:30 minute video answers the question: I have had my second COVID-19 vaccine shot. Can I throw away my mask and begin visiting with family and friends?

Orange County Health Director, Quintana Stewart, answers this question.
VIDEO: EnglishFLYER: English, Español, Chinese, Arabic, Burmese, Karen, Swahili
Screen Shot 2020-12-30 at 2.54.05 PM Opens in new windowScreen Shot 2020-12-30 at 2.54.22 PM Opens in new window
Flyer in EnglishFlyer in Spanish

Making it Plain: BCAC

Making it Plain: A conversation with Dr. Fauci
Community Immunity
Community Immunity 1: Let's All Get the Vaccine feat. Darryl DMC McDaniels
Gladys Knight
#MyReasonWNC​ Gladys Knight
NC Basketball asking
North Carolina's college basketball programs are asking you to take your COVID-19 shot
Former Presidents and First Ladies
Former Presidents & First Ladies: ‘It’s Up To You’ :60 | Ad Council and COVID Collaborative
My Shot
My Shot: A COVID Vaccine Adaption
How do mRNA vaccines work?  John Hopkins Bloomberg School of Public Health

How do mRNA vaccines work? John Hopkins Bloomberg School of Public Health
Reverend Darryl Warren Aaron of Greensboro
Reverend Darryl Warren Aaron of Greensboro encourages everyone, particularly historically marginalized populations, to get the COVID-19 vaccine once it's their turn.
Black Issues Forum
Black Issues Forum UNC TV Jan 8 2021 with Ben Money Dept. Sec. of Health Services
Cafecito con El Condado de Orange
Español - Confianza / Trust
Español - Mitos y Realidades / Myths and Facts
Español - Mente Sana / Mental Health
Español - Las Vacunas contra la COVID-19 / COVID-19 Vaccines
Older North Carolinians, You Have A Spot, Take Your Shot
Older North Carolinians: You Have A Spot, Take Your Shot
Message to Older Adults from Former Governor Jim Hunt
Message to Older Adults from Former Governor Jim Hunt

 HEALTH WEB HEADERS_jan26_202113

The Orange County Health Department and the Orange County Emergency Operations Center are planning for the distribution and administration of the COVID-19 vaccine. The Health Department will receive direct allocations of vaccine to be administered in the community.

Part of this local planning effort includes compiling a list of persons and organizations interested and willing to assist in mass vaccinations. Please complete this form to be added to the roster of staff at a mass vaccination site (Point of Dispensing). Please note some of the positions available require a certified or licensed healthcare professional and you will need to provide a copy of your active certification or license. Additional communications and training will be provided after registering. You will be contacted soon after you submit your information.

Please direct any questions you may have about this survey to the Emergency Operations Center Planning Section at or visit:

KUDOS to Community Volunteers

Kudos   Praise or give a compliment for something well done. Kudos can be given to thank or congratulate a person, team, or group for their efforts. 

Nominate Volunteers – Please show gratitude to the wonderful volunteers who are working hard to make community COVID-19 vaccination possible! Use this form.

Kudos march 1 2021 Opens in new window